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Yet, in a recent trial in patients with chronic obstructive pulmonary disease (COPD), oral administration of sulforaphane for four weeks failed to induce the expression of Nrf2, NQO-1, and HO-1 in alveolar macrophages, bronchial epithelial cells, or peripheral blood mononuclear cells (17)

Having said that, its just simply not always possible or feasible to get all of your nutrients from food which is why supplements exist

Reported side effects are mild, local, and temporary: occasional redness, stinging, or breakouts during initial use

Sulforaphane as an inducer of glutathione prevents oxidative stress-induced cell death in a dopaminergic-like neuroblastoma cell line